tert-Butyl ((3S,4R)

tert-Butyl ((3S,4R) - Names and Identifiers

Name	tert-Butyl (3S,4R)-4-phenylpyrrolidin-3-ylcarbamate
Synonyms	tert-Butyl ((3S,4R) -4-phenylpyrrolidin-3-yl) TRANS-3-N-BOC-AMINO-4-PHENYLPYRROLIDINE tert-Butyl (3S,4R)-4-phenylpyrrolidin-3-ylcarbamate tert-Butyl [(3S,4R)-4-phenylpyrrolidin-3-yl]carbamate TERT-BUTYL [(3S,4R)-4-PHENYLPYRROLIDIN-3-YL]CARBAMATE (4-PHENYLPYRROLIDIN-3-YL)CARBAMIC ACID TERT-BUTYL ESTER tert-Butyl N-[(3R,4S)-4-phenylpyrrolidin-3-yl]carbamate carbamic acid, N-[(3S,4R)-4-phenyl-3-pyrrolidinyl]-, 1,1-dimethylethyl ester
CAS	351360-61-7
InChI	InChI=1/C15H22N2O2/c1-15(2,3)19-14(18)17-13-10-16-9-12(13)11-7-5-4-6-8-11/h4-8,12-13,16H,9-10H2,1-3H3,(H,17,18)/t12-,13+/m0/s1

tert-Butyl ((3S,4R) - Physico-chemical Properties

Molecular Formula	C15H22N2O2
Molar Mass	262.35
Density	1.09±0.1 g/cm3(Predicted)
Boling Point	401.1±45.0 °C(Predicted)
Flash Point	196.4°C
Vapor Presure	1.21E-06mmHg at 25°C
pKa	12.10±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.543

tert-Butyl ((3S,4R) - Introduction

tert-Butyl (3S,4R)-is an organic compound with the chemical formula C16H24N2O2. Here is some information about the compound:

Nature:
-Appearance: Colorless or yellowish solid
-Melting point: about 40-42°C
-Boiling point: about 402°C
-Solubility: Soluble in ammonia, alcohol and ketone solvents, insoluble in water
-Optical activity: chiral molecules with 3S,4R configuration

Use:
- tert-Butyl (3S,4R)-often used in organic synthesis reactions as a derivative of a chiral inducer or catalyst.
-It also has certain application value in the field of drug research, and can be used to prepare drugs or drug precursors containing chiral intermediates.

Preparation Method:
The synthesis method of tert-Butyl (3S,4R)-is more complicated and mainly includes the following steps:
1. First, benzoic acid and pyrrolidine are reacted to form (3S,4R)-4-phenylpyrrolidine.
2. Then, (3S,4R)-4-phenylpyrrolidine is reacted with tert-butanol and dibutyl carbonate to generate the target product.

Safety Information:
- tert-Butyl (3S,4R)-Specific safety information such as toxicity and irritation has not been clearly reported, but general chemical handling and storage safety regulations should be followed.
-Wear appropriate protective equipment, such as lab gloves, goggles, and lab coats, when conducting experiments with this compound.
-When handling this compound, care should be taken to avoid contact with the skin, eyes, and inhalation of its dust or gas to avoid adverse reactions.
-During storage, it should be kept in a cool, dry place away from fire and acid.

it should be noted that this is only a general description of the compound, and the specific experimental operation and safety measures should be carried out according to the specific situation and professional guidance. If you need to use this compound, please do it under the guidance of a laboratory safety expert.

Last Update：2024-04-09 21:01:54